TEKRABber manuscript submitted to bioRxiv

We submitted our manuscript on our study of functional relationships between KRAB-ZNF genes and transposable elements (TEs) to bioRxiv: “Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease”. In this work, Yao and Arnaud discovered that gene expression as well as regulation of TEs differs in the human brain compared to other primates. It also has changed in individuals with Alzheimer’s disease. To perform this comparative assessment of TE:KRAB-ZNF relationships, Yao developed an R package, called TEKRABber, which is publicly available on Bioconductor.